Topic:AI-Driven Analysis and Understanding of Life-Science Omics Data
Speaker:Asst. Prof. Zhuohan Yu (School of Artificial Intelligence, Jilin University)
Abstract
With the rapid development of high-throughput technologies such as single-cell sequencing and spatial omics, life science research is gradually expanding from the analysis of individual molecular features toward the identification of cell states, the characterization of tissue spatial structure and the understanding of complex molecular regulatory mechanisms. Massive, multi-source and high-dimensional life-science omics data offer new research opportunities for revealing the principles of biological activity and the mechanisms underlying complex diseases, while also placing higher demands on AI methods in terms of representational capacity, analytical accuracy and biological interpretability. Existing methods for processing omics data, however, still face challenges such as data sparsity and noise interference, the difficulty of accurately identifying complex cell states, the difficulty of effectively characterizing spatial tissue relationships, and insufficient linkage of multi-level biological information. To address these issues, this talk presents our series of research advances in AI-driven analysis and understanding of life-science omics data, focusing on cell state representation, learning of tissue spatial structure and identification of key biological features. It discusses the application of AI techniques such as graph representation learning and deep learning to the analysis of complex life-science omics data, offering new computational methods and research perspectives for a deeper understanding of cell function, tissue organization and disease-related biological mechanisms.
Speaker Bio
Zhuohan Yu is an Assistant Professor and doctoral supervisor at the School of Artificial Intelligence, Jilin University. His current research interests mainly include single-cell omics analysis, spatial omics computing and biomedical artificial intelligence. He has published more than 10 papers in renowned journals and conferences at home and abroad, includingNature Communications,Advanced Science,Briefings in Bioinformaticsand AAAI. He leads one project under the National Natural Science Foundation of China (NSFC) Young Student Basic Research Program, and was selected for the Young Elite Scientists Sponsorship Program (Doctoral Student Track) of the China Association for Science and Technology. He also serves as a reviewer for journals includingAdvanced Science,Genome Biology,Genome Medicineand TKDE.
Time:Wednesday, October 28, 2026, 15:30–17:10
Venue:Undergraduate Classroom, 4th Floor, Zhengxin Building, Qianwei Campus, Jilin University
